9:00am Welcome
Suzanne Tomlinson-Mathis, Gulf Coast Consortia
Ken Chen, MD Anderson Cancer Center
Moderator: Julea Vlassakis, Rice University
9:10-9:50 Keynote Presentation
Deciphering the Achilles Heal of Cancer Immunotherapy Through the Lenses of Single-Cell Genomics
Alexandra-Chloe Villani, Harvard University
9:50-10:20 Vendor Session-Pre Function and Event Hall
Moderator: Ken Chen, MD Anderson Cancer Center
Session 1: Single Cell Analysis for Cancer Therapeutics
10:20-10:40 Modulating Cancer Antigen Presentation to Potentiate Immunotherapy
Shengqing Gu, MD Anderson Cancer Center
10:40-11:00 Learning Tumor-Immune Interactions Through a Single Cell Spatial Proteomic Atlas in Gastrointestinal Cancers
Anil Korkut, MD Anderson Cancer Center
11:00-11:15 Characterizing the Transcriptional State of Residual Tumors in Triple Negative Breast Cancer
Abhinaya Ganesan, Baylor College of Medicine
Moderator: Julea Vlassakis, Rice University
11:15-11:50 Lighting poster talks
Sohini Banerjee, Baylor College of Medicine
Infants and Adult Human Intestinal Enteroids Are Distinct Model Systems of the Gastrointestinal Epithelium Poster 1
Timothy Bi, MD Anderson Cancer Center
Decontaminating Single-Cell Mitochondrial Mutations After Hematopoietic Stem Cell Transplant Poster 2
Shreyan Gupta, Texas A&M University
Mapping Gene Influence by Single-Cell Perturbation Response Scanning Poster 3
Loukia Karacosta, MD Anderson Cancer Center
Monitoring Therapy Resistance in Longitudinal SCLC Liquid Biopsies with Mass Cytometry Poster 4
Atulya Mandyam, Baylor College of Medicine
Single-Cell ATAC-seq Atlas of the Human Optic Nerve and Optic Nerve Head Poster 5
Ryan Mulqueen, MD Anderson Cancer Center
Towards a Single-Cell Methylation Atlas of Early Breast Cancer Events Poster 6
Andrew Pountain, University of Texas Health Science Center at Houston
Bacterial Transcription-Replication Interactions: a Model System for Quantitative Analysis of Global Gene Expression Poster 7
Edgar Ruiz, Rice University
Native Single-Cell PAGE to Detect Cancer-Associated Heterogenous Protein-Protein Interaction Networks Poster 8
Gerda Cristal Villalba Silva, Baylor College of Medicine
Multi-Omic Single Cell Atlas of the Human Optic Nerve and Optic Nerve Head Poster 9
Luqiong Wang, Baylor College of Medicine
Decoding Human Norovirus Tropism via Single-Cell RNA Analysis Poster 10
11:50-1:45 Lunch and Poster Session-Event Hall
11:50-12:45 Lunch
12:45-2:00 Posters
Moderators: Nick Navin, MD Anderson Cancer Center
2:00-2:40 Keynote Presentation
Tumor Initiation and Progression in Brca1 Mutant Breast Cancer
Devon Lawson, Univ. of California, Irvine
Moderators: Guangyu Wang, Houston Methodist Research Institute
Session 2: Integrating Engineered Biological Models with Single-Cell and Spatial Analysis
2:40-3:00 Single Cell and Spatial Omics to Understand Neural Fate Decisions in the Hindbrain
Jessica Butts, Rice University
3:00-3:20 Molecular Insights into Human Brain Organoid Metabolism using Mass Spectrometry Imaging
Miriana Maletic-Savatic, Baylor College of Medicine
3:20-3:35 Leveraging AI to Reveal Spatial Heterogeneity, Cellular Interactions, and Drug Response
Qianqian Song, University of Florida
3:35-4:05 Vendor Session-Pre Function and Event Hall
Session 3: Beyond the Transcriptome
Moderators: Guy Nir, University of Texas Medical Branch Galveston
4:05-4:25 Single-Cell Models of Trianscriptome-Translatome Interactions for Improved Cell Fate Prediction
Kristopher Brannan, Houston Methodist Research Institute
4:25-4:45 Dissecting Acute Myeloid Leukemia: Insights from Single-Cell Epigenetic Accessibility and Immune Repertoires
Hussein Abbas, MD Anderson Cancer Center
4:45-5:00 Identifying Cancerous Chromosomal Rearrangements with High Spatial and Genomic Resolution
Caitlin Czinder, MD Anderson Cancer Center
5:00-5:05 pm Closing Remarks and drawing
5:05-6:00 Reception-Pre Function